The chemokine receptor CXCR4 and its ligand CXCL12 regulate leukocyte trafficking. homeostasis and functions and are potential therapeutic targets in many diseases such as HIV-1 infection and cancers. Here. we identified new CXCR4 ligands in the CERMN chemical library using a FRET-based high-throughput screening assay. https://www.alexmatia.com/product-category/wovn-botmshorts/
Discovery of Bis-Imidazoline Derivatives as New CXCR4 Ligands
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